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- Effect of PTEN antagonist peptide on the functional motor recovery in rat
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- Moving beyond the glial scar for spinal cord repair
- The Struggle to Make CNS Axons Regenerate: Why Has It Been so Difficult?
- The potential of electric field for promoting neurite guidance in spinal cord injury regeneration strategies
- Extraction and selective activation of muscle synergies through spinal stimulation for SCI
- Early limb unloading elicits long-term motor deficits involving motorneuron hyperexcitability associated with persistent alterations in glutamatergic synaptic plasticity in spinal cord injury
- The effects of a pro-angiogenic, RGD-functionalized, nanofiber composite biomaterial on mesenchymal stem cell-mediated repair of the injured spinal cord
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Tag Archives: LAR
Dr. Jerry Silver, PhD. – Presents Research Updates from 2011 Nerve Bridging Project at Working 2 Walk 2012
These online video presentations from the W2W 2012 symposium are only made possible through your generous contributions to U2FP. Jerry Silver, PhD. Professor, Department of Neurosciences, Case Western Reserve University “Functional Regeneration Into and Well Beyond the Glial Scar” Dr. … Continue reading
Posted in Advocacy, Chronic Spinal Cord Injury Research, Neuroscience Abstracts, Regenerative Medicine, Rehabilitation, spinal cord injury research, Stem Cell Research
Tagged academic researchers, advocacy, axon regeneration, Case Western Reserve University, Ch'ase, Chondroitinase ABC, chronic spinal cord injury, clinical trials, clinical trials spinal cord injury, corticospinal tract, CSPG scar degradation, Dr. Jerry Silver, FDA, LAR, locomotion, nerve bridging, neurite growth, NIH, paralysis, peptide, proteoglycans, spinal cord injury research, U2FP, Unite 2 Fight Paralysis, Working 2 Walk 2012
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Dr. Jerry Silver, PhD: Functional Recovery with Peptides – Presents at Working 2 Walk 2012
These online video presentations from the W2W 2012 symposium are only made possible through your generous contributions to U2FP. Jerry Silver, PhD, Professor, Department of Neurosciences, Case Western Reserve University “Functional Recovery after SCI with the use of Injectable Peptides … Continue reading
Posted in Advocacy, Chronic Spinal Cord Injury Research, Gene Therapy, Regenerative Medicine, Rehabilitation, spinal cord injury research, Stem Cell Research
Tagged advocacy, axon regeneration, Case Western Reserve University, Ch'ase, Chondroitinase ABC, chronic spinal cord injury, clinical trials spinal cord injury, Dr. Jerry Silver, ILP, ISP, LAR, locomotion, motor function, nerve bridging, neurite growth, paralysis, peptide, proteoglycans, PTEN, regeneration, spinal cord injury research, stem cells, U2FP, Unite 2 Fight Paralysis, Working 2 Walk 2012
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Inhibitors of Axonal Growth – Neural Prosthesis Seminar at Case Western Reserve University
Speaker: Roman Giger, Phd University of Michigan Date: October 4, 2012
Posted in Chronic Spinal Cord Injury Research, Neuroscience Abstracts, Regenerative Medicine
Tagged biochemistry, Case Westerm Reserve University, Ch'ase, Condroitinase ABC, CSPG scar degradation, Dr. Jerry Silver, GAG side chains, Hep'ase, LAR, Ligand, myelin, neurite outgrowth, Nogo, Roman Giger, RPTP Sigma
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Peptide inhibitors of LAR family phosphatases release CSPG mediated entrapment of axons and promote robust behavioral recovery following contusive spinal cord injury.
This cutting edge progressive scientific research project being undertaken by Dr. Jerry Silver at Case Western Reserve University and his collaborative team are now moving into chronic spinal cord injury models. This is a project being supported by UNITE 2 … Continue reading
Posted in Neuroscience Abstracts
Tagged axonal regeneration, Case Western Reserve University, Chondroitinase ABC, chronic spinal cord injury, CSPG, distrophic axon, Dr. Jerry Silver, glia scar, growth cones, LAR, locomotor, peptides, Protein Tyrosine Phosphatase-Sigma (PTPσ), PTP, unprecedented levels of functional recovery
Comments Off on Peptide inhibitors of LAR family phosphatases release CSPG mediated entrapment of axons and promote robust behavioral recovery following contusive spinal cord injury.