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- Stroke Drug Boosts Stem Cell Therapy For Spinal Cord Injury In Rats
- An integrated in silico pipeline identifies a novel TF combination that promotes enhanced CST growth following injury
- Spike timing-dependent plasticity in the adult rat with chronic cervical spinal cord contusion
- Effect of PTEN antagonist peptide on the functional motor recovery in rat
- GDF10 promotes axonal regeneration and functional recovery: A novel gene therapy strategy for spinal cord injury
- GTX Medical and NeuroRecovery Technologies to merge
- Candidate Therapy From Quebec for Chronic SCI Being Developed in Parallel by Academics and Companies in Switzerland and the Netherlands
- Moving beyond the glial scar for spinal cord repair
- The Struggle to Make CNS Axons Regenerate: Why Has It Been so Difficult?
- The potential of electric field for promoting neurite guidance in spinal cord injury regeneration strategies
- Extraction and selective activation of muscle synergies through spinal stimulation for SCI
- Early limb unloading elicits long-term motor deficits involving motorneuron hyperexcitability associated with persistent alterations in glutamatergic synaptic plasticity in spinal cord injury
- The effects of a pro-angiogenic, RGD-functionalized, nanofiber composite biomaterial on mesenchymal stem cell-mediated repair of the injured spinal cord
- From wheelchair to walking after spinal cord injury
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Tag Archives: CSPG scar degradation
Modulation of CSPG Receptor Promotes Locomotor and Urinary Recovery – Dr. Jerry Silver
Dr. Silver presents findings from his lab’s discovery that peptide modulation of the CSPG receptor PTP allowed for remarkable recovery of hindlimb function, locomotor activity, and bladder control in 17 of 20 animals. (Courtesy presentation and video provided by Unite … Continue reading
Posted in Chronic Spinal Cord Injury Research, Regenerative Medicine, spinal cord injury research
Tagged Case Western Reserve University, CSPG scar degradation, Dr. Jerry Silver, Protein Tyrosine Phosphatase-Sigma (PTPσ)
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Dr. Jerry Silver and Dr. Yu-Shang Lee: “Nerve Regeneration Restores Supraspinal Control of Bladder Function after Complete Spinal Cord Injury”
A couple years ago Dr. Jerry Silver of Case Western Reserve University in Cleveland achieved a big leap in regenerative medicine for spinal cord injury with his work on Functional Regeneration of Respiratory Pathways After Spinal Cord Injury showing that … Continue reading
Posted in Advocacy, Chronic Spinal Cord Injury Research, Neuroscience Abstracts, Regenerative Medicine, Rehabilitation, spinal cord injury research
Tagged academic researchers, axon regeneration, Case Western Reserve University, Ch'ase, Chondroitinase ABC, chronic spinal cord injury, corticospinal tract, CSPG scar degradation, Dr. Jerry Silver, Dr. Yu-Shang Lee, locomotion, neurite growth, paralysis, regeneration, U2FP, Unite 2 Fight Paralysis, Unite2FightParalysis, Working 2 Walk 2012
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Improving Transmission in Damaged Spinal Cord to Promote Recovery of Function
SCIRP 2012 Investigator Vignette Title: Improving Transmission in Damaged Spinal Cord to Promote Recovery of Function After Spinal Cord Injury Investigator: Victor Arvanian, PhD, DSi; Northport Veterans Affairs Medical Center So the outline of this grant is that the most … Continue reading
Posted in Chronic Spinal Cord Injury Research, Regenerative Medicine, spinal cord injury research
Tagged axon regeneration, Ch'ase, Chondroitinase ABC, chronic spinal cord injury, CSPG scar degradation, Dr. Joel Levine, Dr. Victor Arvanian, locomotion, NG2, proteoglycans, regeneration, spinal cord injury research
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What The Community Wants To Know! Dr. Justin Brown and Dr. Jerry Silver Answer Questions About Building Bridges and Restored Function at Working 2 Walk 2012
These online video presentations from the W2W 2012 symposium are only made possible through your generous contributions to U2FP. ADDITIONAL INFORMATION: Dr. Justin M. Brown ADDITIONAL INFORMATION: Dr. Jerry Silver
Posted in Advocacy, Chronic Spinal Cord Injury Research, Regenerative Medicine, Rehabilitation, spinal cord injury research
Tagged axon regeneration, Case Western Reserve University, Chondroitinase ABC, chronic spinal cord injury, clinical trials spinal cord injury, CSPG scar degradation, Dr. Jerry Silver, nerve bridging, nerve grafting, nerve transfer, regeneration, U2FP, Unite 2 Fight Paralysis, Unite2FightParalysis, Working 2 Walk 2012
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Dr. Jerry Silver, PhD. – Presents Research Updates from 2011 Nerve Bridging Project at Working 2 Walk 2012
These online video presentations from the W2W 2012 symposium are only made possible through your generous contributions to U2FP. Jerry Silver, PhD. Professor, Department of Neurosciences, Case Western Reserve University “Functional Regeneration Into and Well Beyond the Glial Scar” Dr. … Continue reading
Posted in Advocacy, Chronic Spinal Cord Injury Research, Neuroscience Abstracts, Regenerative Medicine, Rehabilitation, spinal cord injury research, Stem Cell Research
Tagged academic researchers, advocacy, axon regeneration, Case Western Reserve University, Ch'ase, Chondroitinase ABC, chronic spinal cord injury, clinical trials, clinical trials spinal cord injury, corticospinal tract, CSPG scar degradation, Dr. Jerry Silver, FDA, LAR, locomotion, nerve bridging, neurite growth, NIH, paralysis, peptide, proteoglycans, spinal cord injury research, U2FP, Unite 2 Fight Paralysis, Working 2 Walk 2012
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ISRT picks up two chronic paralysis research projects from presentations at the Working 2 Walk 2012 Symposium
Perhaps some of the most exciting developments that occur from the annual Working 2 Walk Symposium are scientific collaborations and partnerships built by Unite 2 Fight Paralysis. Two of the presenters at the 2012 symposium held in Irvine California in … Continue reading
Posted in Advocacy, Biomaterials, Chronic Spinal Cord Injury Research, Gene Therapy, Regenerative Medicine, spinal cord injury research
Tagged Ch'ase, Chondroitinase ABC, chronic spinal cord injury, clinical trials spinal cord injury, corticospinal tract, CSPG scar degradation, Dr. Murray Blackmore, Dr. Ravi Bellamkonda, ISRT, neurite growth, spinal cord injury research, Spinal Cord Injury Research, U2FP, Unite 2 Fight Paralysis, Working 2 Walk 2012
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Dr. Arthur Brown, PhD – Targeting gene regulation to promote plasticity and repair.
Dr. Arthur Brown, PhD, Scientist, Robarts Research Institute, Associate Professor, Anatomy and Cell Biology, Western University. Targeting gene regulation to promote plasticity and repair in the injured spinal cord. Published on Nov 26, 2012 by WesternUniversity
Posted in Chronic Spinal Cord Injury Research, Gene Therapy, Regenerative Medicine, spinal cord injury research, Stem Cell Research
Tagged antagonist, astroycytes, axon regeneration, Brown Lab, calmodulin, Chondroitinase ABC, chronic spinal cord injury, CPZ, CSPG scar degradation, Dr. Arthur Brown, gene delivery, gene expression, gene transcription, GFAP, inflammation, neurological recovery, neurons, paralysis, peptide strategy, PhD, proteoglycans, SOX9, spinal cord injury research, stem cell biology
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Inhibitors of Axonal Growth – Neural Prosthesis Seminar at Case Western Reserve University
Speaker: Roman Giger, Phd University of Michigan Date: October 4, 2012
Posted in Chronic Spinal Cord Injury Research, Neuroscience Abstracts, Regenerative Medicine
Tagged biochemistry, Case Westerm Reserve University, Ch'ase, Condroitinase ABC, CSPG scar degradation, Dr. Jerry Silver, GAG side chains, Hep'ase, LAR, Ligand, myelin, neurite outgrowth, Nogo, Roman Giger, RPTP Sigma
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Gene delivery of chondroitinase ABC promotes functional repair following spinal cord injury
There is new hope for the use of viral delivery of ch’ase (Chondroitinase ABC) as a way to treat a much broader area of the spinal cord and for more (LENGTHY TIME PERIODS) (LINK) Because contusive lesions are so large … Continue reading
Posted in Gene Therapy, Neuroscience Abstracts
Tagged Case Western Reserve University, cervical contustion, Ch'ase, ChABC, Chondroitinase ABC, contusive injury, CSPG scar degradation, Dr. Jerry Silver, Dr. Liz Bradbury, functional repair, gene delivery, grip strength, motor function, research, sensory function, spinal cord injury
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SPINAL CORD INJURY RESEARCH AND SCIENCE 