- Miracle chemical ‘cocktail’ could cure spinal cord damage
- Combined expression of pro-regenerative transcription factors and transplanted stem cells to promote corticospinal tract regeneration.
- Structural and Functional Substitution of Deleted Primary Sensory Neurons by New Growth from Intrinsic Spinal Cord Nerve Cells: An Alternative Concept in Reconstruction of Spinal Cord Circuits
- U2FP SCI CureCast now includes the 8th episode!
- Chronic SCI: ReNetX Bio Launched to Advance Innovative Neuro-Regenerative Technology Developed at Yale University
- Overexpression of KLF6 in corticospinal tract neurons promotes axon growth after spinal injury
- A potent anti-spastic effect after intrathecal NK1 antisense oligonucleotide or subpial AAV9-NK1-ShRNA delivery in rats with chronic spinal transection-induced muscle spasticity
- Non-Invasive Paired Stimulation and Anklebot Robot to Improve Lower Extremity Motor Recovery in Chronic Spinal Cord Injury
- Spinal cord injury: Using cortical targets to improve motor function
- 43 Disability Protesters outside of Senate Mitch McConnell’s office arrested over proposed severe Medicaid cuts.
- Interaction of reactive astrocytes with type I collagen induces astrocytic scar formation through the integrin–N-cadherin pathway after SCI
- SCI Stem-cell pioneer enters the political field in California
- Patients with Complete Paralysis Show Additional Recovery of Arm, Hand and Finger Function at 9-months After Treatment with Asterias’ AST-OPC1
- Induction of immune tolerance by short-course immunosuppresion after spinal grafting of allogeneic neural precursors in pigs with previous chronic spinal cord traumatic injury.
- Growth Hormone Improves Sensory Function in Complete Spinal Injury
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Category Archives: Gene Therapy
By Stephen Beech, SWNS A chemical “cocktail” could restore movement for people crippled after suffering spinal cord injuries, suggests new research. Scientists say the mixture of three molecules could potentially be given therapeutically to patients to aid in their recovery … Continue reading
Combined expression of pro-regenerative transcription factors and transplanted stem cells to promote corticospinal tract regeneration.
The failure of axon regeneration in the injured spinal cord results in partial or complete loss of function distal to the injury. To restore the function, severed axons must regrow and functionally reconnect to appropriate targets below the injury site. … Continue reading
Axonal regeneration in the central nervous system is limited in part by a developmental decline in the intrinsic regenerative capacity of central nervous system (CNS) neurons. Changes in gene expression are likely involved, and thus transcription factors that orchestrate gene … Continue reading
Researchers have found a genetic signature located exclusively in the nerve cells that supply, or innervate, the muscles of an organism’s outermost extremities: the hands and feet. This signature, observed in both mice and chicks, involves the coordinated activity of … Continue reading
FULL ARTICLE LINK: Genetic Engineering and Biotechnology News Keep the Opportunities, Lose the Opportunists Authors: Graham Parker, Ph.D. and Jeanne F. Loring, Ph.D. A recent article focused attention on the proliferation of unregulated clinics in the U.S. that promise stem … Continue reading
From the Michael Lane Lab Website “With a primary focus on pre-clinical research, our long-term goal is to develop strategies for improving functional outcome after cervical spinal cord injury (SCI)” More than 20 years ago, a group of faculty members … Continue reading
Jeffrey Petruska, PhD, of the UofL Kentucky Spinal Cord Injury Research Center, describes his research of the mechanisms controlling adult axon growth. Dr. Petruska has received funding from KBRIN and collaborated with the KBRIN Bioinformatics team on this study. He … Continue reading
How the use of genomic information can inform treatments for patients, including the use of neural stem cells to generate axonal growth. Dr. Mark Tuszynski
A Marquette University researcher hopes his work could be a promising step towards a cure for spinal cord injuries. Dr. Murray Blackmore turned to an unlikely ally in his work – cancer genes. Current medical practices cannot heal a spinal … Continue reading
Samuel L. Pfaff, Ph.D. Development of Spinal Cord Connections That Underlie Movement Probing the Depths: under the Sea and into the Brain A serious spinal cord injury is a life-changing experience. It impairs movement and limits sensation and can result … Continue reading