Category Archives: spinal cord injury research

Translational Regenerative Therapies for Chronic Spinal Cord Injury

Authors: Kyriakos Dalamagkas, Magdalini Tsintou, Amelia Seifalian, Alexander M. Seifalian Abstract: “Spinal cord injury is a chronic and debilitating neurological condition that is currently being managed symptomatically with no real therapeutic strategies available. Even though there is no consensus on the best time … Continue reading

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Biomimetic 3D-printed scaffolds for spinal cord injury repair

Authors: Jacob Koffler, Wei Zhu, Xin Qu, Oleksandr Platoshyn, Jennifer N. Dulin, John Brock, Lori Graham, Paul Lu, Jeff Sakamoto, Martin Marsala, Shaochen Chen, Mark H. Tuszynski “Current methods for bioprinting functional tissue lack appropriate biofabrication techniques to build complex 3D micro architectures essential for guiding cell … Continue reading

Posted in Biomaterials, Chronic Spinal Cord Injury Research, Regenerative Medicine, spinal cord injury research, Stem Cell Research | Tagged , , , , , , , , , , , | 2 Comments

Calcium imaging of synaptic connectivity between host and neural progenitor cell graft-derived neurons after spinal cord injury

Authors: STEVEN L. CETO, K. SEKIGUCHI, A. NIMMERJAHN, M. H. TUSZYNSKI; Lab Abstract: Neural stem cells (NSCs) grafted into sites of spinal cord injury (SCI) may act as new electrophysiological relays between host neurons above and below the lesion. Host … Continue reading

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Regaining trunk stability after spinal cord injury

Authors: M. RATH, D. G. SAYENKO, Y. P. GERASIMENKO, V. EDGERTON Lab Abstract: Recently we have developed the non-invasive electrical spinal stimulation technology for postural control in SCI subjects during standing. However, the potential of non-invasive spinal stimulation to facilitate … Continue reading

Posted in Chronic Spinal Cord Injury Research, Neuroscience Abstracts, Rehabilitation, spinal cord injury research | Tagged , | 6 Comments

Human Oligodendrogenic Neural Progenitor Cells Delivered with Chondroitinase ABC Facilitate Functional Repair of Chronic Spinal Cord Injury

Authors: Satoshi Nori, Mohamad Kahazaei, Christopher S. Ahuja, Kazuya Yokota, Jan-Eric Ahlfors, Yang Liu, Jain Wang, Shinsuke Shibata, Jonathon Chio, Marian H Hettiaratchi, Tobias Fuhrmann, Molly S. Shoichet, Michael G. Gehlings Summary: “Treatment of chronic spinal cord injury (SCI) is … Continue reading

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Inhibition of miR-383 promotes axon regeneration following injury

Authors: C. JUZWIK, B. MORQUETTE, Y. ZHANG, E. GOWING, C. BOUDREAU-PINSONNEAULT, V. VANGOOR, R. PASTERKAMP, C. MOORE, A. BAR-OR, A. E. FOURNIER Lab Abstract: Neuroinflammation can positively influence axon regeneration following injury in the central nervous system (CNS) but the … Continue reading

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Epidural Spinal Cord Stimulation Acutely Modulates Lower Urinary Tract and Bowel Function Following Spinal Cord Injury: A Case Report

Authors: Matthias Walter, Amanda H. X. Lee, Alex Kavanagh, Aaron A. Phillips and Andrei V. Krassioukov “Regaining control of autonomic functions such as those of the cardiovascular system, lower urinary tract and bowel, rank among the most important health priorities … Continue reading

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SCI Research starts a big New Year

In preparation for the February NIH SCI 2020,  this is the LINK you will be using to watch the meeting live on the day of the event.   https://videocast.nih.gov/ Tuesday February 12th at 8:AM Eastern Time Wednesday February 13th at 8:00 AM … Continue reading

Posted in Chronic Spinal Cord Injury Research, spinal cord injury research

Dustin Shillcox explains epidural stimulation that restores movement after SCI

“In 2013, Dustin Shillcox became 1 of the first 4 people in the world to be a part of groundbreaking epidural stimulation research at the University of Louisville.  A set of electrodes was surgically implanted onto his spinal cord below the level of his injury and a … Continue reading

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Continued development of human neural stem cell grafts into non-human primate spinal cord contusion or hemisection lesions

Authors: *E. S. ROSENZWEIG, J. H. BROCK, P. LU, H. KUMAMARU, J. L. WEBER, C. A. WEINHOLTZ, R. MOSEANKO, S. HAWBECKER, R. PENDER, C. L. CRUZEN, E. A. SALEGIO,, J. HUIE, C. ALMEIDA, Y. S. NOUT-LOMAS, L. A. HAVTON, A. … Continue reading

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