Category Archives: spinal cord injury research

Opinion: Ethical Challenges in Using iPS Cells to Treat Paralysis

Uncertainties about the cells’ risk profiles and the potential for hyping unproven therapies mean scientists and the media must tread carefully. On February 18, 2019, The Asahi Shimbun reported, “Ministry [of Health, Labor and Welfare in Japan] OKs 1st iPS [induced … Continue reading

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Mechanisms of noradrenergic modulation of synaptic transmission and neuronal excitability in ventral horn neurons of the rat spinal cord

Authors: H. SHOJI, M. OHASHI, T. HIRANO, K. WATANABE, N. ENDO, T. KOHNO Lab Abstract: “Noradrenaline (NA) modulates the spinal motor networks for locomotion and facilitates neuroplasticity, both of which are important for neural recovery in the subacute and chronic … Continue reading

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Marquette receives $500,000 for research from the Bryon Riesch Foundation

The Bryon Riesch Paralysis Foundation pledged Feb. 15 to donate $500,000 to Marquette’s College of Health Sciences to fund research, particularly that of Murray Blackmore, an associate professor of biomedical sciences. Blackmore’s lab studies spinal cord injuries, but more specifically studies gene … Continue reading

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NERVGEN PHARMA COMPLETES $10 MILLION INITIAL PUBLIC OFFERING

Vancouver, Canada. March 13, 2019 – NervGen Pharma Corp. (“NervGen” or the “Company”), a regenerative medicine company dedicated to creating innovative solutions for the treatment of nerve damage, today announced that it has completed its initial public offering (“IPO”) of … Continue reading

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Acteoside Improves Muscle Atrophy and Motor Function by Inducing New Myokine Secretion in Chronic Spinal Cord Injury

Authors: Kodani A1, Kikuchi T1, Tohda C1. Division of Neuromedical Science, Institute of Natural Medicine, University of Toyama, Toyama, Japan Lab Abstract: Chronic spinal cord injury (SCI) is difficult to cure, even by several approaches effective at the acute or subacute phase. We … Continue reading

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Restoring function after severe spinal cord injury through bioluminescence-driven optogenetic stimulation of spinal circuitry

Authors: E. D. PETERSEN, A. PAL, J. ZENCHAK, E. D. SHARKEY, L. SHAFAU, A. PENA, M. PRAKASH, U. HOCHGESCHWENDER; Central Michigan Univ., Mount Pleasant, MI Lab Team Abstract: The ability to manipulate specific neuronal populations of the spinal cord following … Continue reading

Posted in Biomaterials, Chronic Spinal Cord Injury Research, Neuromodulation, Neuroscience Abstracts, Rehabilitation, spinal cord injury research | Tagged , , | Leave a comment

Repositioning Flubendazole for Spinal Cord Injury

Authors: Yu CG1, Bondada V2, Ghoshal S3, Singh R4, Pistilli CK5, Dayaram K6, Iqbal H7, Sands M8, Davis K9, Bondada S10, Geddes JW11   University of Kentucky Spinal Cord and Brain Injury Research Center Lab Abstract We previously reported the serendipitous observation that Fenbendazole, a benzimidazole anthelmintic, improved functional and pathological … Continue reading

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Regenerative metabolic signaling after nerve and spinal injury

Authors: Elisabeth SERGER, G. KONG, I. PALMISANO, E. MCLACHLAN, S. DI GIOVANNI Lab Abstract: Mammalian axonal regeneration is limited in the injured peripheral nervous system (PNS) occur and it fails in the central nervous system (CNS) such as after a … Continue reading

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Dr Jerry Silver – Spinal Cord Damage and Emerging Treatments

“Injuries to the spinal cord can cause permanent paralysis and even lead to death, with little to no hope of regaining lost functions once the trauma has occurred. Dr Jerry Silver and his team at Case Western Reserve University Medical … Continue reading

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Epigenetic regulation of axonal regeneration

Authors: S. DI GIOVANNI, E. MACLACHLAN, I. PALMISANO, T. HUTSON, A. HERVERA, F. DE VIRGILIIS, M. DANZI, J. BIXBY, V. LEMMON Lab Abstract: Regeneration after peripheral nerve injury depends on the activation of key signalling events, the recruitment of transcription … Continue reading

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