Category Archives: Regenerative Medicine

Discovery Offers New Hope to Repair Spinal Cord Injuries

By Dana G. Smith, PhD / Gladstone News / April 24, 2017 Scientists at the Gladstone Institutes created a special type of neuron from human stem cells that could potentially repair spinal cord injuries. These cells, called V2a interneurons, transmit … Continue reading

Posted in Chronic Spinal Cord Injury Research, Neuroscience Abstracts, Regenerative Medicine, Spinal Research, Stem Cell Research | Tagged , , , | 2 Comments

Stretching the boundaries of neural implants

Rubbery, multifunctional fibers could be used to study spinal cord neurons and potentially restore function. David L. Chandler | MIT News Office Implantable fibers have been an enormous boon to brain research, allowing scientists to stimulate specific targets in the … Continue reading

Posted in Biomaterials, Chronic Spinal Cord Injury Research, Regenerative Medicine, Spinal Research | Leave a comment

What Budget Cuts Might Mean for US Science

A look at the historical effects of downsized research funding suggests that the Trump administration’s proposed budget could hit early-career scientists the hardest. By Diana Kwon | March 21, 2017 The Trump administration’s proposed federal budget has already evoked significant … Continue reading

Posted in Chronic Spinal Cord Injury Research, Regenerative Medicine, Rehabilitation, Spinal Research

CITC LTD and partners on personalized stem cell therapies for injury and diseases of the CNS

CITC Ltd has recently concluded a non-esclusive license agreement with Provendis GmbH, a technology transfer agency of 27 universities of North Rhine-Westphalia, including the University of Bonn, for a manufacturing technology of autologous induced neural stem cells (iNSC) from adult … Continue reading

Posted in Chronic Spinal Cord Injury Research, Regenerative Medicine, Spinal Research, Stem Cell Research

Nerve growth At The Extremeties

Researchers have found a genetic signature located exclusively in the nerve cells that supply, or innervate, the muscles of an organism’s outermost extremities: the hands and feet. This signature, observed in both mice and chicks, involves the coordinated activity of … Continue reading

Posted in Chronic Spinal Cord Injury Research, Gene Therapy, Regenerative Medicine, Spinal Research, Stem Cell Research

Paul Knoepfler Stem Blog “The Niche” providing weekly Q & A.

The Niche LINK: Segment 1. Where is the stem cell field now and where the heck is it heading? There are hundreds of questions. Readers often email me questions or leave them as comments. It’s not unusual to get questions … Continue reading

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Assessment of the combined effects of chondroitinase and autologous Schwann cells on hand function after cervical SCI in primates

Abstract Introduction: Chondroitinase ABC and Schwann cells have been shown independently to promote functional recovery in rodents after contusive injury. Autologous human Schwann cells ahSC are being tested in Phase 1 clinical trials for sub-acute and chronic SCI. Recognizing the … Continue reading

Posted in Chronic Spinal Cord Injury Research, Neuroscience Abstracts, Regenerative Medicine, Rehabilitation, Spinal Research, Stem Cell Research

Comparative transcriptomic analysis of sprouting and regenerating corticospinal neurons

Abstract The corticospinal tract (CST) is a critical motor system in humans for voluntary movement. The inability of adult corticospinal axons to spontaneously regenerate after spinal cord injury (SCI) may be attributable in part to incomplete activation of neuronal growth … Continue reading

Posted in Chronic Spinal Cord Injury Research, Neuroscience Abstracts, Regenerative Medicine, Spinal Research

Short and long term effects of neural progenitor transplantation following cervical spinal cord contusion injury

Video and Abstract: Impaired breathing is a devastating consequence of cervical spinal cord injury (SCI) that increases morbidity and the risk of mortality. Injuries at high-to-mid cervical levels (C1-4) result in the most severe deficits as the phrenic motor circuitry … Continue reading

Posted in Chronic Spinal Cord Injury Research, Neuroscience Abstracts, Regenerative Medicine, Spinal Research, Stem Cell Research | Tagged , ,

Working 2 Walk 2016 Panel Discussion with Dr. Ann Parr and Dr. Alex Aimetti

The audience at the Working 2 Walk Symposium asks questions about the presentations of Dr. Parr and Dr. Aimetti. Alex Aimetti, PhD, is Senior Director, Medical Education and Scientific Support at InVivo Therapeutics. InVivo is a research and clinical-stage biomaterials … Continue reading

Posted in Biomaterials, Chronic Spinal Cord Injury Research, Regenerative Medicine, Spinal Research, Stem Cell Research, Unite 2 Fight Paralysis, Working 2 Walk Science & Advocacy Symposium | Tagged , | 2 Comments