Category Archives: Regenerative Medicine

Identifying the most effective types of integration-free human iPS cell-derived neural stem/progenitor cells in the treatment of spinal cord injury

Identifying the most effective types of integration-free human iPS cell-derived neural stem/progenitor cells in the treatment of spinal cord injury Authors: T. IIDA, N. NAGOSHI, J. KOHYAMA, O. TSUJI, M. MATSUMOTO, M. NAKAMURA, H. OKANO Lab Abstract: INTRODUCTION: We have … Continue reading

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Perspectives on “the biology of spinal cord regeneration success and failure”

Neural Regeneration Research Journal Authors: Philippa Mary Warren, Amanda Phuong Tran, and Jerry Silver, Ph.D. “In our recently co-authored Physiological Reviews manuscript entitled “The biology of regeneration failure and success after spinal cord injury” (Tran et al., 2018b), we sought … Continue reading

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Three prong approach bridges complete SCI in rodents

EPFL (Ecole polytechnique fédérale de Lausanne) in Switzerland and UCLA (University of California in Los Angeles, California) have collaborated in making severed nerve fibers  regenerate across a complete SCI to form a bridge in rodents.  Their three part recipe for … Continue reading

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Work towards finding the right stem cell for SCI therapy

I recently read a wonderful paper published in Nature addressing a stem cell experiment  for spinal cord injury.  This paper is very scientifically detailed, but they show the need for having the right age and origin of stem cell to … Continue reading

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An informative CSPG article out of Robarts Research Institute

One of the important strategies that labs have been focusing on for spinal cord injury has been how to best deal with CSPG (chondroitin sulfate proteoglycans) commonly known as the scar that builds up at the site of injury (lesion) … Continue reading

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Stem cell lab work continues to show progress

Even though we may be years away from a robust stem cell treatment coming to the market for spinal cord injury, the lab work continues to progress and show great promise.  What we don’t know is; which stem cell will … Continue reading

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New strategy with small molecules found for potential complementary therapy to treat SCI

Read this Full Story at Science Digest HERE Most people with spinal cord injury are paralyzed from the injury site down, even when the cord isn’t completely severed. Why don’t the spared portions of the spinal cord keep working? Researchers … Continue reading

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Worldwide licensing agreement made on peptide developed in Silver laboratory at Case Western Reserve University

Read the Full Article at Globe Newswire.   VANCOUVER, British Columbia, July 18, 2018 (GLOBE NEWSWIRE) — NervGen Pharma Corp. (“NervGen”), in Vancouver, and Case Western Reserve University (“Case Western Reserve”) in Cleveland have entered into an exclusive worldwide licensing agreement to research, develop and … Continue reading

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In a Break with Dogma, Myelin Boosts Neuron Growth in Spinal Cord Injuries

The molecule inhibits adult axon regeneration, but appears to stimulate young neurons by Scott LaFee Recovery after severe spinal cord injury is notoriously fraught, with permanent paralysis often the result. In recent years, researchers have increasingly turned to stem cell-based … Continue reading

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A new microtubule-based approach for augmenting nerve regeneration

Most studies on microtubules in the nervous system have focused on the dynamic properties of the microtubules, with stabilization by taxol and related drugs being proposed as a therapeutic for nerve injury. However, while initial indications were hopeful, more recent … Continue reading

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