Category Archives: Regenerative Medicine

Stroke Drug Boosts Stem Cell Therapy For Spinal Cord Injury In Rats

Posted on December 17, 2019 by christalpowell

Four months after treating them, Yasuhiro Shiga, MD, PhD, checked on his rats. Walking into the lab, he carried minimal expectations. Treating spinal cord injuries with stem cells had been tried by many people, many times before, with modest success … Continue reading →

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Effect of PTEN antagonist peptide on the functional motor recovery in rat

Posted on November 4, 2019 by christalpowell

Authors: *S. LV1, W. WU2; 1 Guangdong-hongkong-Macau Inst. of CNS Regeneration, Guangzhou, China; 2 The Univ.Of Hong Kong, Hong Kong SAR, Hong Kong Lab Abstract: Ventral root injury results in great loss of motor functions because of the inefficient axon … Continue reading →

Posted in Chronic Spinal Cord Injury Research, Neuroscience Abstracts, Regenerative Medicine, spinal cord injury research | 1 Comment

Moving beyond the glial scar for spinal cord repair

Posted on September 8, 2019 by christalpowell

Authors: Elizabeth J. Bradbury and Emily R. Burnside Abstract: Traumatic spinal cord injury results in severe and irreversible loss of function. The injury triggers a complex cascade of inflammatory and pathological processes, culminating in formation of a scar. While traditionally … Continue reading →

Posted in Chronic Spinal Cord Injury Research, Regenerative Medicine, spinal cord injury research | Tagged , | 1 Comment

Regeneration of Spinal Cord Connectivity Through Stem Cell Transplantation and Biomaterial Scaffolds

Posted on June 16, 2019 by christalpowell

Authors: Hiroyuki Katoh, Kazuya Yokota and Michael Fehlings “In this review, we outline the pathophysiology of SCI that makes the spinal cord refractory to regeneration and discuss the research that has been done with cell replacement and biomaterial implantation strategies, … Continue reading →

Posted in Biomaterials, Chronic Spinal Cord Injury Research, Gene Therapy, Regenerative Medicine, spinal cord injury research, Stem Cell Research | Tagged , , | 1 Comment

Putting 3D Printing to Work to Heal Spinal Cord Injury

Posted on June 9, 2019 by christalpowell

“For people whose spinal cords are injured in traffic accidents, sports mishaps, or other traumatic events, cell-based treatments have emerged as a potential avenue for encouraging healing. Now, taking advantage of advances in 3D printing technology, researchers have created customized … Continue reading →

Posted in Biomaterials, Regenerative Medicine, spinal cord injury research, Stem Cell Research | Tagged | 1 Comment

Interfering with Semaphorin3A in perineuronal nets to enhance plasticity

Posted on June 2, 2019 by christalpowell

Authors: D. CARULLI, R. BROERSEN, F. DE WINTER, H.-J. BOELE, B. HOBO, C. CANTO, E. M. MUIR, C. I. DE ZEEUW, J. VERHAAGEN Lab Abstract: Neuronal plasticity is crucial for our brain to learn, adapt to the environment and recover … Continue reading →

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Strategies for Regeneration | Arthur Brown |

Posted on May 19, 2019 by christalpowell

Dr. Brown will guide a discussion of how the brain is naturally able to recover from damage through the process of neuroplasticity – the ability to rewire circuits, so as to compensate for lost function. Further delving in to his … Continue reading →

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NervGen looking to use their technology to revolutionize nerve damage treatment

Posted on April 12, 2019 by christalpowell

NervGen Pharma (CVE:NGEN) President and CEO Ernest Wong sat down with Steve Darling from Proactive Investors Vancouver to talk about the pharma company that has technology that hopes to regenerate nerve damage, that damage can be spinal cord or peripheral. … Continue reading →

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Enhancement of plasticity for functional recovery after spinal cord injury

Posted on April 7, 2019 by christalpowell

Authors: S. F. IRVINE, S. GIGOUT, P. M. WARREN, J. C. F. KWOK Lab Abstract: To promote recovery after spinal cord injury (SCI), treatments aim to enhance regeneration of severed axons and the plasticity of surviving circuitry. Enzymatic removal of … Continue reading →

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Mechanisms of noradrenergic modulation of synaptic transmission and neuronal excitability in ventral horn neurons of the rat spinal cord

Posted on March 17, 2019 by christalpowell

Authors: H. SHOJI, M. OHASHI, T. HIRANO, K. WATANABE, N. ENDO, T. KOHNO Lab Abstract: “Noradrenaline (NA) modulates the spinal motor networks for locomotion and facilitates neuroplasticity, both of which are important for neural recovery in the subacute and chronic … Continue reading →

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