Author Archives: christalpowell

Coronavirus today and the SCI community tomorrow

Posted on March 8, 2020 by christalpowell

I’m not going to sugar coat the Coronavirus situation. Even as I begin writing this post, the numbers continue to grow geometrically for new coronavirus cases around the world. The day started out with around 460 cases in the USA … Continue reading →

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Stroke Drug Boosts Stem Cell Therapy For Spinal Cord Injury In Rats

Posted on December 17, 2019 by christalpowell

Four months after treating them, Yasuhiro Shiga, MD, PhD, checked on his rats. Walking into the lab, he carried minimal expectations. Treating spinal cord injuries with stem cells had been tried by many people, many times before, with modest success … Continue reading →

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An integrated in silico pipeline identifies a novel TF combination that promotes enhanced CST growth following injury

Posted on November 17, 2019 by christalpowell

Authors *I. VENKATESH1, Z. WANG2, V. MEHRA1, E. EASTWOOD1, M. SIMPSON1, A. CHAKRABORTY1, D. GROSS1, Z.BEINE1, M. CABAHUG1, G. OLSON1, M. G. BLACKMORE3;2Dept. of Biomed. Sci., 3Biomed. Sci., 1Marquette Univ., Milwaukee, WI Lab Abstract Embryonic and peripheral neurons respond to … Continue reading →

Posted in Chronic Spinal Cord Injury Research, Gene Therapy, Neuroscience Abstracts, spinal cord injury research | Tagged , , | 1 Comment

Spike timing-dependent plasticity in the adult rat with chronic cervical spinal cord contusion

Posted on November 10, 2019 by christalpowell

Authors: *N. DE LA OLIVA1, A. E. HAGGERTY1, M. A. PEREZ1,2, M. OUDEGA1,2,3,4; 1 Miami Project To Cure Paralysis, Univ. of Miami, Miami, FL; 2 Bruce W. Carter Dept. of Veterans Affairs Med. Ctr., Miami, FL; 3 Affiliated Cancer Hosp. … Continue reading →

Posted in Chronic Spinal Cord Injury Research, Neuromodulation, Neuroscience Abstracts, Rehabilitation, spinal cord injury research | 1 Comment

Effect of PTEN antagonist peptide on the functional motor recovery in rat

Posted on November 4, 2019 by christalpowell

Authors: *S. LV1, W. WU2; 1 Guangdong-hongkong-Macau Inst. of CNS Regeneration, Guangzhou, China; 2 The Univ.Of Hong Kong, Hong Kong SAR, Hong Kong Lab Abstract: Ventral root injury results in great loss of motor functions because of the inefficient axon … Continue reading →

Posted in Chronic Spinal Cord Injury Research, Neuroscience Abstracts, Regenerative Medicine, spinal cord injury research | 1 Comment

GDF10 promotes axonal regeneration and functional recovery: A novel gene therapy strategy for spinal cord injury

Posted on October 24, 2019 by christalpowell

Authors:*P. M. ABDUL-MUNEER, S. BHOWMICK, V. D’MELLO; Hackensack Meridian Hlth. JFK Med. Ctr., Edison, NJ Neuroscience 2019 LINK Lab Abstract: Spinal cord injury (SCI) occurs when there is damage from trauma, loss of normal blood supply, or a mass effect … Continue reading →

Posted in Chronic Spinal Cord Injury Research, Gene Therapy, Neuroscience Abstracts, spinal cord injury research, Stem Cell Research | Tagged , , | 1 Comment

GTX Medical and NeuroRecovery Technologies to merge

Posted on October 22, 2019 by christalpowell

GTX Medical and NeuroRecovery Technologies today announced their merger into a global company for the development of neuromodulation therapies for spinal cord injuries. The two merging companies plan to develop the targeted epidural spine stimulation system, an implantable spinal cord … Continue reading →

Posted in Chronic Spinal Cord Injury Research, Neuromodulation, Rehabilitation, spinal cord injury research | Tagged , | 3 Comments

Candidate Therapy From Quebec for Chronic SCI Being Developed in Parallel by Academics and Companies in Switzerland and the Netherlands

Posted on October 13, 2019 by christalpowell

QUEBEC CITY, CANADA, October 10th 2019 – Today, Laboratoires Guertin announces that a campaign for funding has been launched to support a phase IIb-enabling pilot study with a tritherapy candidate (buspirone/L-DOPA/carbidopa)called Spinalon. This experimental oral pill has been shown to … Continue reading →

Posted in Chronic Spinal Cord Injury Research, Neuromodulation, Rehabilitation, spinal cord injury research | Tagged | 6 Comments

Moving beyond the glial scar for spinal cord repair

Posted on September 8, 2019 by christalpowell

Authors: Elizabeth J. Bradbury and Emily R. Burnside Abstract: Traumatic spinal cord injury results in severe and irreversible loss of function. The injury triggers a complex cascade of inflammatory and pathological processes, culminating in formation of a scar. While traditionally … Continue reading →

Posted in Chronic Spinal Cord Injury Research, Regenerative Medicine, spinal cord injury research | Tagged , | 1 Comment

The Struggle to Make CNS Axons Regenerate: Why Has It Been so Difficult?

Posted on September 1, 2019 by christalpowell

Author: James W. Fawcett Abstract: Axon regeneration in the CNS is inhibited by many extrinsic and intrinsic factors. Because these act in parallel, no single intervention has been sufficient to enable full regeneration of damaged axons in the adult mammalian … Continue reading →

Posted in Chronic Spinal Cord Injury Research, Gene Therapy, Ligand, spinal cord injury research, Stem Cell Research | Tagged | Comments Off on The Struggle to Make CNS Axons Regenerate: Why Has It Been so Difficult?