Category Archives: Neuroscience Abstracts

Extraction and selective activation of muscle synergies through spinal stimulation for SCI

Authors: *R. CHENG, J. W. BURDICK; Lab Abstract: Epidural spinal stimulation (ESS) has been shown to enable recovery of motor control in patients with clinically complete spinal cord injury (SCI). It is hypothesized that this results from activation of postural … Continue reading

Posted in Chronic Spinal Cord Injury Research, Neuromodulation, Neuroscience Abstracts, Rehabilitation, spinal cord injury research | Tagged , , | 2 Comments

Early limb unloading elicits long-term motor deficits involving motorneuron hyperexcitability associated with persistent alterations in glutamatergic synaptic plasticity in spinal cord injury

Authors: *K. MORIOKA1,2, T. TAZOE3,2, J. HUIE1,4, J. HAEFELI1, C. A. ALMEIDA1, J. A. SACRAMENTO1, J. C. BRESNAHAN1, M. S. BEATTIE1, S. TANAKA5, T. OGATA2, A. R. FERGUSON1,4; Lab Abstract: Abnormal sensory afferent feedback from the lower extremities after spinal … Continue reading

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The effects of a pro-angiogenic, RGD-functionalized, nanofiber composite biomaterial on mesenchymal stem cell-mediated repair of the injured spinal cord

Abstract: Spinal cord injury (SCI) results in nervous tissue loss and so far untreatable functional impairments. Preclinical studies have demonstrated that a transplant of bone marrow-derived mesenchymal stem cells (MSCs) elicits paracrine effects resulting in anatomical repair and partial functional … Continue reading

Posted in Biomaterials, Chronic Spinal Cord Injury Research, Neuroscience Abstracts, spinal cord injury research, Stem Cell Research | Tagged , ,

Interfering with Semaphorin3A in perineuronal nets to enhance plasticity

Authors: D. CARULLI, R. BROERSEN, F. DE WINTER, H.-J. BOELE, B. HOBO, C. CANTO, E. M. MUIR, C. I. DE ZEEUW, J. VERHAAGEN Lab Abstract: Neuronal plasticity is crucial for our brain to learn, adapt to the environment and recover … Continue reading

Posted in Chronic Spinal Cord Injury Research, Gene Therapy, Neuroscience Abstracts, Regenerative Medicine, spinal cord injury research | Tagged ,

Strategies for Regeneration | Arthur Brown |

Dr. Brown will guide a discussion of how the brain is naturally able to recover from damage through the process of neuroplasticity – the ability to rewire circuits, so as to compensate for lost function. Further delving in to his … Continue reading

Posted in Chronic Spinal Cord Injury Research, Neuroscience Abstracts, Regenerative Medicine, spinal cord injury research | Tagged ,

Combined administration of electro-magnetic stimulation (EMS) at spinal level and at leg muscles to modulate neurophysiological properties at spino-muscular circuitry in healthy and SCI humans

Authors: V. L. ARVANIAN, H. A. PETROSYAN, A. TESFA, M. FAHMY, C. ZOU, S. SISTO Lab Abstract: H-reflex is recognized as an important neurophysiology tool used in evaluation of spino-muscular circuitry. H-reflex is sensitive to conditions and activity. For example, … Continue reading

Posted in Chronic Spinal Cord Injury Research, Neuromodulation, Neuroscience Abstracts, Rehabilitation, spinal cord injury research | Tagged , | 1 Comment

Enhancement of plasticity for functional recovery after spinal cord injury

Authors: S. F. IRVINE, S. GIGOUT, P. M. WARREN, J. C. F. KWOK Lab Abstract: To promote recovery after spinal cord injury (SCI), treatments aim to enhance regeneration of severed axons and the plasticity of surviving circuitry. Enzymatic removal of … Continue reading

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Edonerpic maleate boosts motor function recovery from spinal cord injury

Authors: M. SATO, S. JITSUKI, H. MASUYAMA, H. MURATA, T. YAMAMOTO, T. TAKAHASHI Lab Abstract: Spinal cord injury (SCI) is a miserable neurological condition that often causes permanent sensory, motor, and bladder-bowel dysfunction. Despite the needs of treatments, clinical options … Continue reading

Posted in Chronic Spinal Cord Injury Research, Neuroscience Abstracts, spinal cord injury research | 2 Comments

Mechanisms of noradrenergic modulation of synaptic transmission and neuronal excitability in ventral horn neurons of the rat spinal cord

Authors: H. SHOJI, M. OHASHI, T. HIRANO, K. WATANABE, N. ENDO, T. KOHNO Lab Abstract: “Noradrenaline (NA) modulates the spinal motor networks for locomotion and facilitates neuroplasticity, both of which are important for neural recovery in the subacute and chronic … Continue reading

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Acteoside Improves Muscle Atrophy and Motor Function by Inducing New Myokine Secretion in Chronic Spinal Cord Injury

Authors: Kodani A1, Kikuchi T1, Tohda C1. Division of Neuromedical Science, Institute of Natural Medicine, University of Toyama, Toyama, Japan Lab Abstract: Chronic spinal cord injury (SCI) is difficult to cure, even by several approaches effective at the acute or subacute phase. We … Continue reading

Posted in Chronic Spinal Cord Injury Research, Neuroscience Abstracts, spinal cord injury research | Tagged , , , , | 2 Comments