Category Archives: Neuroscience Abstracts

An integrated in silico pipeline identifies a novel TF combination that promotes enhanced CST growth following injury

Posted on November 17, 2019 by christalpowell

Authors *I. VENKATESH1, Z. WANG2, V. MEHRA1, E. EASTWOOD1, M. SIMPSON1, A. CHAKRABORTY1, D. GROSS1, Z.BEINE1, M. CABAHUG1, G. OLSON1, M. G. BLACKMORE3;2Dept. of Biomed. Sci., 3Biomed. Sci., 1Marquette Univ., Milwaukee, WI Lab Abstract Embryonic and peripheral neurons respond to … Continue reading →

Posted in Chronic Spinal Cord Injury Research, Gene Therapy, Neuroscience Abstracts, spinal cord injury research | Tagged , , | 1 Comment

Spike timing-dependent plasticity in the adult rat with chronic cervical spinal cord contusion

Posted on November 10, 2019 by christalpowell

Authors: *N. DE LA OLIVA1, A. E. HAGGERTY1, M. A. PEREZ1,2, M. OUDEGA1,2,3,4; 1 Miami Project To Cure Paralysis, Univ. of Miami, Miami, FL; 2 Bruce W. Carter Dept. of Veterans Affairs Med. Ctr., Miami, FL; 3 Affiliated Cancer Hosp. … Continue reading →

Posted in Chronic Spinal Cord Injury Research, Neuromodulation, Neuroscience Abstracts, Rehabilitation, spinal cord injury research | 1 Comment

Effect of PTEN antagonist peptide on the functional motor recovery in rat

Posted on November 4, 2019 by christalpowell

Authors: *S. LV1, W. WU2; 1 Guangdong-hongkong-Macau Inst. of CNS Regeneration, Guangzhou, China; 2 The Univ.Of Hong Kong, Hong Kong SAR, Hong Kong Lab Abstract: Ventral root injury results in great loss of motor functions because of the inefficient axon … Continue reading →

Posted in Chronic Spinal Cord Injury Research, Neuroscience Abstracts, Regenerative Medicine, spinal cord injury research | 1 Comment

GDF10 promotes axonal regeneration and functional recovery: A novel gene therapy strategy for spinal cord injury

Posted on October 24, 2019 by christalpowell

Authors:*P. M. ABDUL-MUNEER, S. BHOWMICK, V. D’MELLO; Hackensack Meridian Hlth. JFK Med. Ctr., Edison, NJ Neuroscience 2019 LINK Lab Abstract: Spinal cord injury (SCI) occurs when there is damage from trauma, loss of normal blood supply, or a mass effect … Continue reading →

Posted in Chronic Spinal Cord Injury Research, Gene Therapy, Neuroscience Abstracts, spinal cord injury research, Stem Cell Research | Tagged , , | 1 Comment

Extraction and selective activation of muscle synergies through spinal stimulation for SCI

Posted on July 14, 2019 by christalpowell

Authors: *R. CHENG, J. W. BURDICK; Lab Abstract: Epidural spinal stimulation (ESS) has been shown to enable recovery of motor control in patients with clinically complete spinal cord injury (SCI). It is hypothesized that this results from activation of postural … Continue reading →

Posted in Chronic Spinal Cord Injury Research, Neuromodulation, Neuroscience Abstracts, Rehabilitation, spinal cord injury research | Tagged , , | 2 Comments

Early limb unloading elicits long-term motor deficits involving motorneuron hyperexcitability associated with persistent alterations in glutamatergic synaptic plasticity in spinal cord injury

Posted on July 7, 2019 by christalpowell

Authors: *K. MORIOKA1,2, T. TAZOE3,2, J. HUIE1,4, J. HAEFELI1, C. A. ALMEIDA1, J. A. SACRAMENTO1, J. C. BRESNAHAN1, M. S. BEATTIE1, S. TANAKA5, T. OGATA2, A. R. FERGUSON1,4; Lab Abstract: Abnormal sensory afferent feedback from the lower extremities after spinal … Continue reading →

Posted in Chronic Spinal Cord Injury Research, Neuromodulation, Neuroscience Abstracts, spinal cord injury research | Tagged , , | Comments Off on Early limb unloading elicits long-term motor deficits involving motorneuron hyperexcitability associated with persistent alterations in glutamatergic synaptic plasticity in spinal cord injury

The effects of a pro-angiogenic, RGD-functionalized, nanofiber composite biomaterial on mesenchymal stem cell-mediated repair of the injured spinal cord

Posted on June 30, 2019 by christalpowell

Abstract: Spinal cord injury (SCI) results in nervous tissue loss and so far untreatable functional impairments. Preclinical studies have demonstrated that a transplant of bone marrow-derived mesenchymal stem cells (MSCs) elicits paracrine effects resulting in anatomical repair and partial functional … Continue reading →

Posted in Biomaterials, Chronic Spinal Cord Injury Research, Neuroscience Abstracts, spinal cord injury research, Stem Cell Research | Tagged , , | Comments Off on The effects of a pro-angiogenic, RGD-functionalized, nanofiber composite biomaterial on mesenchymal stem cell-mediated repair of the injured spinal cord

Interfering with Semaphorin3A in perineuronal nets to enhance plasticity

Posted on June 2, 2019 by christalpowell

Authors: D. CARULLI, R. BROERSEN, F. DE WINTER, H.-J. BOELE, B. HOBO, C. CANTO, E. M. MUIR, C. I. DE ZEEUW, J. VERHAAGEN Lab Abstract: Neuronal plasticity is crucial for our brain to learn, adapt to the environment and recover … Continue reading →

Posted in Chronic Spinal Cord Injury Research, Gene Therapy, Neuroscience Abstracts, Regenerative Medicine, spinal cord injury research | Tagged , | Comments Off on Interfering with Semaphorin3A in perineuronal nets to enhance plasticity

Strategies for Regeneration | Arthur Brown |

Posted on May 19, 2019 by christalpowell

Dr. Brown will guide a discussion of how the brain is naturally able to recover from damage through the process of neuroplasticity – the ability to rewire circuits, so as to compensate for lost function. Further delving in to his … Continue reading →

Posted in Chronic Spinal Cord Injury Research, Neuroscience Abstracts, Regenerative Medicine, spinal cord injury research | Tagged , | Comments Off on Strategies for Regeneration | Arthur Brown |

Combined administration of electro-magnetic stimulation (EMS) at spinal level and at leg muscles to modulate neurophysiological properties at spino-muscular circuitry in healthy and SCI humans

Posted on May 5, 2019 by christalpowell

Authors: V. L. ARVANIAN, H. A. PETROSYAN, A. TESFA, M. FAHMY, C. ZOU, S. SISTO Lab Abstract: H-reflex is recognized as an important neurophysiology tool used in evaluation of spino-muscular circuitry. H-reflex is sensitive to conditions and activity. For example, … Continue reading →

Posted in Chronic Spinal Cord Injury Research, Neuromodulation, Neuroscience Abstracts, Rehabilitation, spinal cord injury research | Tagged , | 1 Comment