Category Archives: Neuroscience Abstracts

Strategies for Regeneration | Arthur Brown |

Dr. Brown will guide a discussion of how the brain is naturally able to recover from damage through the process of neuroplasticity – the ability to rewire circuits, so as to compensate for lost function. Further delving in to his … Continue reading

Posted in Chronic Spinal Cord Injury Research, Neuroscience Abstracts, Regenerative Medicine, spinal cord injury research | Tagged , | Leave a comment

Combined administration of electro-magnetic stimulation (EMS) at spinal level and at leg muscles to modulate neurophysiological properties at spino-muscular circuitry in healthy and SCI humans

Authors: V. L. ARVANIAN, H. A. PETROSYAN, A. TESFA, M. FAHMY, C. ZOU, S. SISTO Lab Abstract: H-reflex is recognized as an important neurophysiology tool used in evaluation of spino-muscular circuitry. H-reflex is sensitive to conditions and activity. For example, … Continue reading

Posted in Chronic Spinal Cord Injury Research, Neuromodulation, Neuroscience Abstracts, Rehabilitation, spinal cord injury research | Tagged , | 1 Comment

Enhancement of plasticity for functional recovery after spinal cord injury

Authors: S. F. IRVINE, S. GIGOUT, P. M. WARREN, J. C. F. KWOK Lab Abstract: To promote recovery after spinal cord injury (SCI), treatments aim to enhance regeneration of severed axons and the plasticity of surviving circuitry. Enzymatic removal of … Continue reading

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Edonerpic maleate boosts motor function recovery from spinal cord injury

Authors: M. SATO, S. JITSUKI, H. MASUYAMA, H. MURATA, T. YAMAMOTO, T. TAKAHASHI Lab Abstract: Spinal cord injury (SCI) is a miserable neurological condition that often causes permanent sensory, motor, and bladder-bowel dysfunction. Despite the needs of treatments, clinical options … Continue reading

Posted in Chronic Spinal Cord Injury Research, Neuroscience Abstracts, spinal cord injury research | 2 Comments

Mechanisms of noradrenergic modulation of synaptic transmission and neuronal excitability in ventral horn neurons of the rat spinal cord

Authors: H. SHOJI, M. OHASHI, T. HIRANO, K. WATANABE, N. ENDO, T. KOHNO Lab Abstract: “Noradrenaline (NA) modulates the spinal motor networks for locomotion and facilitates neuroplasticity, both of which are important for neural recovery in the subacute and chronic … Continue reading

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Acteoside Improves Muscle Atrophy and Motor Function by Inducing New Myokine Secretion in Chronic Spinal Cord Injury

Authors: Kodani A1, Kikuchi T1, Tohda C1. Division of Neuromedical Science, Institute of Natural Medicine, University of Toyama, Toyama, Japan Lab Abstract: Chronic spinal cord injury (SCI) is difficult to cure, even by several approaches effective at the acute or subacute phase. We … Continue reading

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Restoring function after severe spinal cord injury through bioluminescence-driven optogenetic stimulation of spinal circuitry

Authors: E. D. PETERSEN, A. PAL, J. ZENCHAK, E. D. SHARKEY, L. SHAFAU, A. PENA, M. PRAKASH, U. HOCHGESCHWENDER; Central Michigan Univ., Mount Pleasant, MI Lab Team Abstract: The ability to manipulate specific neuronal populations of the spinal cord following … Continue reading

Posted in Biomaterials, Chronic Spinal Cord Injury Research, Neuromodulation, Neuroscience Abstracts, Rehabilitation, spinal cord injury research | Tagged , ,

Repositioning Flubendazole for Spinal Cord Injury

Authors: Yu CG1, Bondada V2, Ghoshal S3, Singh R4, Pistilli CK5, Dayaram K6, Iqbal H7, Sands M8, Davis K9, Bondada S10, Geddes JW11   University of Kentucky Spinal Cord and Brain Injury Research Center Lab Abstract We previously reported the serendipitous observation that Fenbendazole, a benzimidazole anthelmintic, improved functional and pathological … Continue reading

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Regenerative metabolic signaling after nerve and spinal injury

Authors: Elisabeth SERGER, G. KONG, I. PALMISANO, E. MCLACHLAN, S. DI GIOVANNI Lab Abstract: Mammalian axonal regeneration is limited in the injured peripheral nervous system (PNS) occur and it fails in the central nervous system (CNS) such as after a … Continue reading

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Epigenetic regulation of axonal regeneration

Authors: S. DI GIOVANNI, E. MACLACHLAN, I. PALMISANO, T. HUTSON, A. HERVERA, F. DE VIRGILIIS, M. DANZI, J. BIXBY, V. LEMMON Lab Abstract: Regeneration after peripheral nerve injury depends on the activation of key signalling events, the recruitment of transcription … Continue reading

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