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- Stroke Drug Boosts Stem Cell Therapy For Spinal Cord Injury In Rats
- An integrated in silico pipeline identifies a novel TF combination that promotes enhanced CST growth following injury
- Spike timing-dependent plasticity in the adult rat with chronic cervical spinal cord contusion
- Effect of PTEN antagonist peptide on the functional motor recovery in rat
- GDF10 promotes axonal regeneration and functional recovery: A novel gene therapy strategy for spinal cord injury
- GTX Medical and NeuroRecovery Technologies to merge
- Candidate Therapy From Quebec for Chronic SCI Being Developed in Parallel by Academics and Companies in Switzerland and the Netherlands
- Moving beyond the glial scar for spinal cord repair
- The Struggle to Make CNS Axons Regenerate: Why Has It Been so Difficult?
- The potential of electric field for promoting neurite guidance in spinal cord injury regeneration strategies
- Extraction and selective activation of muscle synergies through spinal stimulation for SCI
- Early limb unloading elicits long-term motor deficits involving motorneuron hyperexcitability associated with persistent alterations in glutamatergic synaptic plasticity in spinal cord injury
- The effects of a pro-angiogenic, RGD-functionalized, nanofiber composite biomaterial on mesenchymal stem cell-mediated repair of the injured spinal cord
- From wheelchair to walking after spinal cord injury
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Tag Archives: Marquette University
An integrated in silico pipeline identifies a novel TF combination that promotes enhanced CST growth following injury
Authors *I. VENKATESH1, Z. WANG2, V. MEHRA1, E. EASTWOOD1, M. SIMPSON1, A. CHAKRABORTY1, D. GROSS1, Z.BEINE1, M. CABAHUG1, G. OLSON1, M. G. BLACKMORE3;2Dept. of Biomed. Sci., 3Biomed. Sci., 1Marquette Univ., Milwaukee, WI Lab Abstract Embryonic and peripheral neurons respond to … Continue reading
Marquette receives $500,000 for research from the Bryon Riesch Foundation
The Bryon Riesch Paralysis Foundation pledged Feb. 15 to donate $500,000 to Marquette’s College of Health Sciences to fund research, particularly that of Murray Blackmore, an associate professor of biomedical sciences. Blackmore’s lab studies spinal cord injuries, but more specifically studies gene … Continue reading
Posted in Chronic Spinal Cord Injury Research, Gene Therapy, Regenerative Medicine, spinal cord injury research
Tagged Bryon Riesch Foundation, Dr. Murray Blackmore, Marquette University
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Marquette professor awarded $1.6 million NIH grant for spinal cord injury research
Marquette University professor Murray Blackmore was awarded a $1.6 million grant from the National Institutes of Health to continue his research of spinal cord injury and paralysis. Dr. Murray Blackmore, associate professor of biomedical sciences in the College of Health … Continue reading
Posted in Chronic Spinal Cord Injury Research, Regenerative Medicine, spinal cord injury research, Stem Cell Research
Tagged Dr. Murray Blackmore, Marquette University
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Combined expression of pro-regenerative transcription factors and transplanted stem cells to promote corticospinal tract regeneration.
The failure of axon regeneration in the injured spinal cord results in partial or complete loss of function distal to the injury. To restore the function, severed axons must regrow and functionally reconnect to appropriate targets below the injury site. … Continue reading
Posted in Chronic Spinal Cord Injury Research, Gene Therapy, Neuroscience Abstracts, Regenerative Medicine, spinal cord injury research, Stem Cell Research
Tagged Dr. Murray Blackmore, Dr. Naveen Jayaprakash, Marquette University
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Overexpression of KLF6 in corticospinal tract neurons promotes axon growth after spinal injury
Axonal regeneration in the central nervous system is limited in part by a developmental decline in the intrinsic regenerative capacity of central nervous system (CNS) neurons. Changes in gene expression are likely involved, and thus transcription factors that orchestrate gene … Continue reading
Could Cancer Genes Help Repair Spinal Cord Injuries?
A Marquette University researcher hopes his work could be a promising step towards a cure for spinal cord injuries. Dr. Murray Blackmore turned to an unlikely ally in his work – cancer genes. Current medical practices cannot heal a spinal … Continue reading
Posted in Chronic Spinal Cord Injury Research, Gene Therapy, Regenerative Medicine, spinal cord injury research
Tagged Bryon Riesch Foundation, Dr. Murray Blackmore, Marquette University
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COMBINED GENETIC/EPIGENETIC MANIPULATIONS TO PROMOTE CST AXON REGENERATION
Combined genetic/epigenetic manipulations to promote CST axon regeneration Embryonic neurons and peripheral neurons respond to axon injury with activation of transcriptional programs conducive to regrowth. In contrast, mature CNS neurons fail to reactivate expression of crucial regeneration associated genes (RAGs) … Continue reading
Posted in Neuroscience Abstracts, spinal cord injury research
Tagged Dr. Murray Blackmore, Ishwariya Venkatesh, Marquette University
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OPTOGENETIC EVALUATION OF FUNCTIONAL SYNAPTIC RECONNECTION BY CORTICOSPINAL TRACT AXONS IN THE INJURED SPINAL CORD
OPTOGENETIC EVALUATION OF FUNCTIONAL SYNAPTIC RECONNECTION BY CORTICOSPINAL TRACT AXONS IN THE INJURED SPINAL CORD Spinal cord injury results in partial or complete loss of neural communication across the site of injury. To restore function, axons must extend into denervated … Continue reading
Posted in Chronic Spinal Cord Injury Research, Neuroscience Abstracts, Regenerative Medicine, spinal cord injury research
Tagged Dr. Murray Blackmore, Dr. Naveen Jayaprakash, Marquette University
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Epigenetic profiling reveals a developmental decrease in promoter accessibility of regeneration associated genes in CNS neurons
Society for Neuroscience Chicago 2015 Central Nervous System Regeneration Transplantation and Regeneration Support: The Bryon Riesch foundation SCIS/U2FP Unite 2 Fight Paralysis Title: Epigenetic profiling reveals a developmental decrease in promoter accessibility of regeneration associated genes in CNS neurons Authors: … Continue reading
Posted in Neuroscience Abstracts
Tagged Dr. Murray Blackmore, Marquette University
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Optogenetic evaluation of functional synaptic reconnection by corticospinal tract axons in the injured spinal cord
Society for Neuroscience Chicago 2015 Spinal Cord Injury: Restorative Strategies Support: NIH Grant NS083983-01 International Spinal Research Trust Title: Optogenetic evaluation of functional synaptic reconnection by corticospinal tract axons in the injured spinal cord Authors: *N. JAYAPRAKASH, B. HOEYNCK, N. … Continue reading
Posted in Neuroscience Abstracts
Tagged Dr. Murray Blackmore, Marquette University
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SPINAL CORD INJURY RESEARCH AND SCIENCE 