- Miracle chemical ‘cocktail’ could cure spinal cord damage
- Combined expression of pro-regenerative transcription factors and transplanted stem cells to promote corticospinal tract regeneration.
- Structural and Functional Substitution of Deleted Primary Sensory Neurons by New Growth from Intrinsic Spinal Cord Nerve Cells: An Alternative Concept in Reconstruction of Spinal Cord Circuits
- U2FP SCI CureCast now includes the 8th episode!
- Chronic SCI: ReNetX Bio Launched to Advance Innovative Neuro-Regenerative Technology Developed at Yale University
- Overexpression of KLF6 in corticospinal tract neurons promotes axon growth after spinal injury
- A potent anti-spastic effect after intrathecal NK1 antisense oligonucleotide or subpial AAV9-NK1-ShRNA delivery in rats with chronic spinal transection-induced muscle spasticity
- Non-Invasive Paired Stimulation and Anklebot Robot to Improve Lower Extremity Motor Recovery in Chronic Spinal Cord Injury
- Spinal cord injury: Using cortical targets to improve motor function
- 43 Disability Protesters outside of Senate Mitch McConnell’s office arrested over proposed severe Medicaid cuts.
- Interaction of reactive astrocytes with type I collagen induces astrocytic scar formation through the integrin–N-cadherin pathway after SCI
- SCI Stem-cell pioneer enters the political field in California
- Patients with Complete Paralysis Show Additional Recovery of Arm, Hand and Finger Function at 9-months After Treatment with Asterias’ AST-OPC1
- Induction of immune tolerance by short-course immunosuppresion after spinal grafting of allogeneic neural precursors in pigs with previous chronic spinal cord traumatic injury.
- Growth Hormone Improves Sensory Function in Complete Spinal Injury
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Tag Archives: Marquette University
Combined expression of pro-regenerative transcription factors and transplanted stem cells to promote corticospinal tract regeneration.
The failure of axon regeneration in the injured spinal cord results in partial or complete loss of function distal to the injury. To restore the function, severed axons must regrow and functionally reconnect to appropriate targets below the injury site. … Continue reading
Axonal regeneration in the central nervous system is limited in part by a developmental decline in the intrinsic regenerative capacity of central nervous system (CNS) neurons. Changes in gene expression are likely involved, and thus transcription factors that orchestrate gene … Continue reading
A Marquette University researcher hopes his work could be a promising step towards a cure for spinal cord injuries. Dr. Murray Blackmore turned to an unlikely ally in his work – cancer genes. Current medical practices cannot heal a spinal … Continue reading
Combined genetic/epigenetic manipulations to promote CST axon regeneration Embryonic neurons and peripheral neurons respond to axon injury with activation of transcriptional programs conducive to regrowth. In contrast, mature CNS neurons fail to reactivate expression of crucial regeneration associated genes (RAGs) … Continue reading
OPTOGENETIC EVALUATION OF FUNCTIONAL SYNAPTIC RECONNECTION BY CORTICOSPINAL TRACT AXONS IN THE INJURED SPINAL CORD
OPTOGENETIC EVALUATION OF FUNCTIONAL SYNAPTIC RECONNECTION BY CORTICOSPINAL TRACT AXONS IN THE INJURED SPINAL CORD Spinal cord injury results in partial or complete loss of neural communication across the site of injury. To restore function, axons must extend into denervated … Continue reading
Epigenetic profiling reveals a developmental decrease in promoter accessibility of regeneration associated genes in CNS neurons
Society for Neuroscience Chicago 2015 Central Nervous System Regeneration Transplantation and Regeneration Support: The Bryon Riesch foundation SCIS/U2FP Unite 2 Fight Paralysis Title: Epigenetic profiling reveals a developmental decrease in promoter accessibility of regeneration associated genes in CNS neurons Authors: … Continue reading
Optogenetic evaluation of functional synaptic reconnection by corticospinal tract axons in the injured spinal cord
Society for Neuroscience Chicago 2015 Spinal Cord Injury: Restorative Strategies Support: NIH Grant NS083983-01 International Spinal Research Trust Title: Optogenetic evaluation of functional synaptic reconnection by corticospinal tract axons in the injured spinal cord Authors: *N. JAYAPRAKASH, B. HOEYNCK, N. … Continue reading
For those watching the gene discovery work in the Blackmore lab at Marquette University, this is good news. Last year, Dr. Blackmore told us about the screening work being done in his lab. Here is the abstract for the publication … Continue reading
Drs. Murray Blackmore and Naveen Jayaprakash tell us about their experiences with the SmartBox. In their efforts to find a cure for spinal cord injury, the Blackmore Lab utilizes an optogenetic approach to study axonal growth in the spinal cords … Continue reading
Dr. Murray Blackmore recently had his research lab bolstered with seed grants and gifts that have led to a 1.6 million dollar grant from the National Institute of Health. The grant will fund continued research into gene therapy reagents and … Continue reading