Tag Archives: CSPG

Non-invasive systemic modulation of the CSPG receptor PTPσ promotes locomotor and urinary recovery following severe contusive spinal cord injury

This poster presentation by Brad Lang was at Society of Neuroscience 2013 in San Diego and took poster honors at the Asilomar Regeneration Conference in Pacific Grove California. Topic: Spinal cord: Therapeutic strategies Authors: *B. T. LANG1, J. M. CREGG1, … Continue reading

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Role of LAR phosphatase in restricting axon regeneration after spinal cord injury

A poster of interest at the Society of Neuroscience 2013. Program#/Poster#: 341.24/AA11 Presentation Title: Role of LAR phosphatase in restricting axon regeneration after spinal cord injury Topic: ++C.11.d. Spinal cord: Cellular and molecular mechanisms Authors: P. ABDUL-MUNEER1, H. LI1, Y. … Continue reading

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Chondroitinase ABC (Ch’ase) a potential future deal maker for Spinal Cord Injuries

Inhibition by scar tissue Following injury, specialised glial cells that normally support neurons accumulate at the injury site and deposit scar tissue. Scar tissue is a major obstacle to spinal cord repair because it creates a physical and biochemical blockage … Continue reading

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Peptide inhibitors of LAR family phosphatases release CSPG mediated entrapment of axons and promote robust behavioral recovery following contusive spinal cord injury.

This cutting edge progressive scientific research project being undertaken by Dr. Jerry Silver at Case Western Reserve University and his collaborative team are now moving into chronic spinal cord injury models. This is a project being supported by UNITE 2 … Continue reading

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