Tag Archives: Dr. Patrick Ganzer

Serotonin receptor and dendritic plasticity in the spinal cord mediated by chronic serotonergic pharmacotherapy combined with exercise following complete SCI in the adult rat

Abstract: Severe spinal cord injury (SCI) damages descending motor and serotonin (5-HT) fiber projections leading to paralysis and serotonin depletion. 5-HT receptors (5-HTRs) subsequently upregulate following 5-HT fiber degeneration, and dendritic density decreases indicative of atrophy. 5-HT pharmacotherapy or exercise can improve locomotor behavior after … Continue reading

Posted in Chronic Spinal Cord Injury Research, Neuroscience Abstracts, Regenerative Medicine, Rehabilitation, spinal cord injury research | Tagged , , , ,

Closed-loop neuromodulation restores network connectivity and motor control after spinal cord injury

Abstract: Recovery from serious neurological injury requires substantial rewiring of neural circuits. Precisely-timed electrical stimulation could be used to restore corrective feedback mechanisms and promote adaptive plasticity after neurological insult, such as spinal cord injury (SCI) or stroke. This study … Continue reading

Posted in Chronic Spinal Cord Injury Research, Neuroscience Abstracts, Rehabilitation, spinal cord injury research | Tagged

Spinal Cord Repair Group Honors Scientist’s Work with VNS Therapy

A group of leading clinicians and experts dedicated to translational research in spinal cord injuries has recognized the work of a research fellow in the Texas Biomedical Device Center at UT Dallas. Based on preclinical studies, vagus nerve stimulation (VNS) … Continue reading

Posted in Chronic Spinal Cord Injury Research, spinal cord injury research | Tagged , ,