Tag Archives: Dr. James Fawcett

The Struggle to Make CNS Axons Regenerate: Why Has It Been so Difficult?

Author: James W. Fawcett Abstract: Axon regeneration in the CNS is inhibited by many extrinsic and intrinsic factors. Because these act in parallel, no single intervention has been sufficient to enable full regeneration of damaged axons in the adult mammalian … Continue reading

Posted in Chronic Spinal Cord Injury Research, Gene Therapy, Ligand, spinal cord injury research, Stem Cell Research | Tagged | Comments Off on The Struggle to Make CNS Axons Regenerate: Why Has It Been so Difficult?

Overexpression of protrudin in primary cortical neurons enhances regeneration after laser axotomy through multiple mechanisms

Authors: V. PETROVA, R.EVA, J.W. FAWCETT Lab Abstract: Numerous extracellular and intracellular processes contribute to the failure of long-range regeneration in the adult central nervous system (CNS) after injury. One reason why adult CNS axons have poor regenerative capabilities is … Continue reading

Posted in Chronic Spinal Cord Injury Research, Neuroscience Abstracts, Regenerative Medicine, spinal cord injury research, Stem Cell Research | Tagged , | Comments Off on Overexpression of protrudin in primary cortical neurons enhances regeneration after laser axotomy through multiple mechanisms