Tag Archives: Chondroitinase

Chondroitinase improves anatomical and functional outcomes after primate spinal cord injury

Lab Abstract: Inhibitory chondroitin sulfate proteoglycans (CSPGs) in the extracellular matrix hinder axonal regeneration after spinal cord injury (SCI). In particular, CSPGs form ‘peri-neuronal nets’ that may limit axonal regrowth and synaptic plasticity. Moreover, CSPGs are newly synthesized at sites … Continue reading

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Dr. Jerry Silver: Latest chronic SCI research results featured at Cleveland FES Neural Prosthesis Seminar

The Silver SCI research lab is dedicated to repairing the chronically injured spinal cord and restoring function after paralysis. The presentation at the Cleveland FES Centers Neural Prosthesis Seminar covers not only the remarkable robust recovery of bladder function but … Continue reading

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“How Pet Dogs Can Help Us Understand the Value of New Therapies for Spinal Cord Injury” Nicholas Jeffery, BVSc, PhD

Pet dogs commonly suffer spinal cord injury, mainly because many small breeds are susceptible to degeneration of their intervertebral discs, which then rupture and cause injury to the spinal cord. Veterinarians treat the resulting spinal cord injury in ways that … Continue reading

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A special message back to Iowa State University College of Veterinary Medicine

The thank you video below features clinical trial patients Frankie, Cooper, Greta and Oscar Madison NYC! They’re participating in the Chondroitinase drug trial for paralyzed dogs at Iowa State College of Veterinary Medicine. A special THANK YOU goes right back … Continue reading

Posted in Chronic Spinal Cord Injury Research, Regenerative Medicine, Rehabilitation, spinal cord injury research | Tagged , , , | 2 Comments

Interview with Dr. Hilary Hu on the Chondroitinase Trial for Spinal Injury at Iowa State

In this two part interview with Dr. Hilary Hu at Iowa State University Veterinary Hospital, learn about spinal cord injuries in dogs and a promising new treatment Dr. Hu and Dr. Nicolas Jeffery are studying for pets with various types … Continue reading

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Large animal trial for Chondroitinase is underway

I usually check into the clinicaltrial.gov website every couple of weeks to review any new human clinical trials for spinal cord injury. However, before some treatments can safely be tested in human clinical trials, they must undergo large animal studies. … Continue reading

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Spinal Research’s Key Objectives for ‘first in man’ studies with Chondroitinase

One of Spinal Research’s key objectives is to identify the quickest and most efficient route to clinical trials. A crucial step in this process has been the approval of a very exciting programme of work to develop the enzyme chondroitinase … Continue reading

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What People are Saying about Working 2 Walk 2012

“These people get it! We all can see the leadership; they lead from the heart.” John O’Connor, Community Member What People are Saying about Working 2 Walk 2012

Posted in Advocacy, Chronic Spinal Cord Injury Research, Gene Therapy, Regenerative Medicine, Rehabilitation, spinal cord injury research | Tagged , , , , , , , , , , , , , , , , , , , , , , , , , ,

The future of chronic spinal cord injury repair – a focus on chondroitinase for clinical trial

Wednesday 7th November 2012 King’s College London At Spinal Research our aim is to find an effective treatment for spinal cord injury that not only improves sensation and movement for people living with paralysis, but brings us closer to a … Continue reading

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