Tag Archives: Bradley Lang

Dr. Jerry Silver: Latest chronic SCI research results featured at Cleveland FES Neural Prosthesis Seminar

The Silver SCI research lab is dedicated to repairing the chronically injured spinal cord and restoring function after paralysis. The presentation at the Cleveland FES Centers Neural Prosthesis Seminar covers not only the remarkable robust recovery of bladder function but … Continue reading

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OPTIMIZATION OF INTRACELLULAR SIGMA PEPTIDE AS A TREATMENT FOR SPINAL CORD INJURY

OPTIMIZATION OF INTRACELLULAR SIGMA PEPTIDE AS A TREATMENT FOR SPINAL CORD INJURY Regeneration and sprouting following spinal cord injury is curtailed by several processes, with the inhibitory chondroitin-sulfate proteoglycan (CSPG)-rich glial scar and peri-neuronal net being major impediments. We designed … Continue reading

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Enhanced regeneration and functional recovery after root avulsion by manipulation of proteoglycan receptor protein tyrosine phosphatase-σ

Society for Neuroscience 2015 Nanosymposium SCI Therapeutic Strategies Trauma Enhanced regeneration and functional recovery after root avulsion by manipulation of proteoglycan receptor protein tyrosine phosphatase-σ Abstract: Following root avulsion, spinal nerves are physically disconnected from the spinal cord. Severe motor … Continue reading

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Intravenous multipotent adult progenitor cell treatment decreases inflammation leading to functional recovery following spinal cord injury

Following spinal cord injury (SCI), immune-mediated secondary injury exacerbates the extent of permanent neurological deficits. We investigated the capacity of adult bone marrow-derived stem cells, which exhibit immunomodulatory properties, to alter inflammatory processes and promote recovery following SCI. In vitro, … Continue reading

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Modulation of the proteoglycan receptor PTPσ induces neuronal protease release to overcome Chondroitin Sulfate Proteoglycan inhibition of axon regeneration

Over the next few weeks I’ll post just a few of the interesting poster abstracts from the Society for Neuroscience conference held in Chicago this year. There’s too many to include them all, however, you’ll get a feel for where … Continue reading

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Update on Experiments to Restore Function after Chronic SCI: Jerry Silver, PhD

The Silver lab is dedicated to the functional repair of the chronically injured spinal cord. We have developed a number of animal models to mimic both complete inury (transection) as well as severe contusive injury (with a small amount of … Continue reading

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Exploradio: Improving the lives of paralyzed people through research

In this week’s Exploradio, WKSU’s Jeff St. Clair meets a Cleveland researcher who’s unlocking the secrets of how to repair a damaged spinal cord. Listen to this weeks radio interview about the research and plans going forward for the latest … Continue reading

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Update on Experiments to Restore Function after Chronic SCI

Dr. Jerry Silver presented the latest information on their chronic research from his lab at Working 2 Walk 2014 in Seattle, WA. The Silver lab is dedicated to the functional repair of the chronically injured spinal cord and this research … Continue reading

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Case Western Reserve University shows off research in ‘science fair on steroids’

Case held a special viewing for local economic development companies such as Jumpstart, BioEnterprise and NorTech on Thursday night.  One project the scouts expressed interest in was by Bradley Lang, a graduate student in neuroscience at Case. Lang is part of … Continue reading

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