Category Archives: spinal cord injury research

Extraction and selective activation of muscle synergies through spinal stimulation for SCI

Posted on July 14, 2019 by christalpowell

Authors: *R. CHENG, J. W. BURDICK; Lab Abstract: Epidural spinal stimulation (ESS) has been shown to enable recovery of motor control in patients with clinically complete spinal cord injury (SCI). It is hypothesized that this results from activation of postural … Continue reading →

Posted in Chronic Spinal Cord Injury Research, Neuromodulation, Neuroscience Abstracts, Rehabilitation, spinal cord injury research | Tagged , , | 2 Comments

Early limb unloading elicits long-term motor deficits involving motorneuron hyperexcitability associated with persistent alterations in glutamatergic synaptic plasticity in spinal cord injury

Posted on July 7, 2019 by christalpowell

Authors: *K. MORIOKA1,2, T. TAZOE3,2, J. HUIE1,4, J. HAEFELI1, C. A. ALMEIDA1, J. A. SACRAMENTO1, J. C. BRESNAHAN1, M. S. BEATTIE1, S. TANAKA5, T. OGATA2, A. R. FERGUSON1,4; Lab Abstract: Abnormal sensory afferent feedback from the lower extremities after spinal … Continue reading →

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The effects of a pro-angiogenic, RGD-functionalized, nanofiber composite biomaterial on mesenchymal stem cell-mediated repair of the injured spinal cord

Posted on June 30, 2019 by christalpowell

Abstract: Spinal cord injury (SCI) results in nervous tissue loss and so far untreatable functional impairments. Preclinical studies have demonstrated that a transplant of bone marrow-derived mesenchymal stem cells (MSCs) elicits paracrine effects resulting in anatomical repair and partial functional … Continue reading →

Posted in Biomaterials, Chronic Spinal Cord Injury Research, Neuroscience Abstracts, spinal cord injury research, Stem Cell Research | Tagged , , | Comments Off on The effects of a pro-angiogenic, RGD-functionalized, nanofiber composite biomaterial on mesenchymal stem cell-mediated repair of the injured spinal cord

From wheelchair to walking after spinal cord injury

Posted on June 25, 2019 by christalpowell

Several paraplegics can now walk again – thanks to precise electrical stimulation of their spinal cords via a wireless implant and intensive neurorehabilitation. Speaking at Science Unlimited 2019, Grégoire Courtine illustrated this incredible spinal implant technology, as well as the … Continue reading →

Posted in Biomaterials, Chronic Spinal Cord Injury Research, Neuromodulation, Rehabilitation, spinal cord injury research | Tagged | Comments Off on From wheelchair to walking after spinal cord injury

ReNetX Bio, Inc. Announces U.S. FDA Authorization to Proceed for IND Application to Treat Patients with Chronic Spinal Cord Injury

Posted on June 23, 2019 by christalpowell

NEW HAVEN, Conn., June 19, 2019 /PRNewswire/ — ReNetX Bio, Inc., a leading biotechnology company committed to reversing disease and damage for patients suffering from central nervous system disorders, has announced that the U.S. Food and Drug Administration (FDA) has allowed the … Continue reading →

Posted in Chronic Spinal Cord Injury Research, spinal cord injury research | Tagged | 2 Comments

Regeneration of Spinal Cord Connectivity Through Stem Cell Transplantation and Biomaterial Scaffolds

Posted on June 16, 2019 by christalpowell

Authors: Hiroyuki Katoh, Kazuya Yokota and Michael Fehlings “In this review, we outline the pathophysiology of SCI that makes the spinal cord refractory to regeneration and discuss the research that has been done with cell replacement and biomaterial implantation strategies, … Continue reading →

Posted in Biomaterials, Chronic Spinal Cord Injury Research, Gene Therapy, Regenerative Medicine, spinal cord injury research, Stem Cell Research | Tagged , , | 1 Comment

Putting 3D Printing to Work to Heal Spinal Cord Injury

Posted on June 9, 2019 by christalpowell

“For people whose spinal cords are injured in traffic accidents, sports mishaps, or other traumatic events, cell-based treatments have emerged as a potential avenue for encouraging healing. Now, taking advantage of advances in 3D printing technology, researchers have created customized … Continue reading →

Posted in Biomaterials, Regenerative Medicine, spinal cord injury research, Stem Cell Research | Tagged | 1 Comment

Interfering with Semaphorin3A in perineuronal nets to enhance plasticity

Posted on June 2, 2019 by christalpowell

Authors: D. CARULLI, R. BROERSEN, F. DE WINTER, H.-J. BOELE, B. HOBO, C. CANTO, E. M. MUIR, C. I. DE ZEEUW, J. VERHAAGEN Lab Abstract: Neuronal plasticity is crucial for our brain to learn, adapt to the environment and recover … Continue reading →

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Strategies for Regeneration | Arthur Brown |

Posted on May 19, 2019 by christalpowell

Dr. Brown will guide a discussion of how the brain is naturally able to recover from damage through the process of neuroplasticity – the ability to rewire circuits, so as to compensate for lost function. Further delving in to his … Continue reading →

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CPAR: Joel Burdick from Caltech on Epidural Spinal Stimulation

Posted on May 12, 2019 by christalpowell

In this video, Joel Burdick peels back the work and strategies that go into making the best algorithms for spinal cord injury stimulation and recovery.  This is a must see!

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