Researchers activate repair program for nerve fibers

Frank Bradke

Frank Bradke Axonal Growth and Regeneration, German Center for Neurodegenerative Diseases, 53175 Bonn, Germany

Bonn (Germany), October 6th, 2016 – Injuries to the spinal cord can cause paralysis and other permanent disabilities because severed nerve fibers do not regrow. Now, scientists of the German Center for Neurodegenerative Diseases (DZNE) have succeeded in releasing a molecular brake that prevents the regeneration of nerve connections. Treatment of mice with Pregabalin, a drug that acts upon the growth inhibiting mechanism, caused damaged nerve connections to regenerate. Researchers led by neurobiologist Frank Bradke report on these findings in the journal Neuron.

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