The Road to Success

Recently posted is a new article with Mark Bacon (Spinal Research Director) in the UK explaining the current efforts in bringing a Chondroitinase human clinical trial forward. The full article can be found HERE.

Key points in the article:

1. We want to create a multidisciplinary, multinational network of experts devoted to spinal cord imaging in a way never seen before and expect to make some major announcements on this soon.

2. We are nearly there and are currently funding a number of groups to develop a clinically-acceptable version.

3. Current gene therapy technology is a bit like a light dimmer switch – we can reduce the gene expression to ‘dim’ but not completely ‘off’. The critical work we are doing now in laboratories is to create a true ‘on/off switch’.

Large-Scale Chondroitin Sulfate Proteoglycan Digestion with Chondroitinase Gene Therapy Leads to Reduced Pathology and Modulates Macrophage Phenotype following Spinal Cord Contusion Injury: ABSTRACT HERE

Gene Therapy Improves Limb Function Following Spinal Cord Injury

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